"It is what we know already that often prevents us from learning."
"I do not ... reject the use of statistics in medicine, but I condemn not trying to get beyond them and believing in statistics as the foundation of medical science. ... Statistics ... apply only to cases in which the cause of the facts observed is still [uncertain or] indeterminate. ... There will always be some indeterminism ... in all the sciences, and more in medicine than in any other. But man's intellectual conquest consists in lessening and driving back indeterminism in proportion as he gains ground for determinism by the help of the experimental method."
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Source: Claude Bernard (2012). “An Introduction to the Study of Experimental Medicine”, p.185, Courier Corporation
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"The experimenter who does not know what he is looking for will not understand what he finds."
"When we meet a fact which contradicts a prevailing theory, we must accept the fact and abandon the theory, even when the theory is supported by great names and generally accepted."
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"Men who have excessive faith in their theories or ideas are not only ill prepared for making discoveries; they also make very poor observations. Of necessity, they observe with a preconceived idea, and when they devise an experiment, they can see, in its results,only a confirmation of their theory. In this way they distort observation and often neglect very important facts because they do not further their aim."