"The great tragedy of science - the slaying of a beautiful hypothesis by an ugly fact."
"It does not matter how many tumbles you have in this life, so long as you do not get dirty when you tumble; it is only the people who have to stop to be washed and made clean, who must necessarily lose the race. And I can assure you that there is the greatest practical benefit in making a few failures early in life. You learn that which is of inestimable importance"
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Source: Thomas Henry Huxley (1893). “Science & education”
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